The epithelial-to-mesenchymal transition (EMT) transcriptional program is characterized by repression of E-cadherin (
Cunxi Li, Haiting Ma, Yang Wang, Zheng Cao, Ramona Graves-Deal, Anne E. Powell, Alina Starchenko, Gregory D. Ayers, Mary Kay Washington, Vidya Kamath, Keyur Desai, Michael J. Gerdes, Lila Solnica-Krezel, Robert J. Coffey
Depletion of endogenous PLAC8 in SC cells restores cell surface CDH1 and reduces ERK2 phosphorylation in xenografts.