Interleukin-17 in inflammatory skin disorders

AJ van Beelen, MBM Teunissen… - Current opinion in …, 2007 - journals.lww.com
AJ van Beelen, MBM Teunissen, ML Kapsenberg, EC de Jong
Current opinion in allergy and clinical immunology, 2007journals.lww.com
In this review, we summarize the current knowledge of IL-17 and Th17 cells and discuss the
possible role of IL-17 in the pathology of psoriasis, contact hypersensitivity and atopic
dermatitis. Whereas IL-17 may play an important role in the pathogenesis of psoriasis and
contact hypersensitivity, its role in atopic dermatitis is still unclear.
Summary
In this review, we summarize the current knowledge of IL-17 and Th17 cells and discuss the possible role of IL-17 in the pathology of psoriasis, contact hypersensitivity and atopic dermatitis. Whereas IL-17 may play an important role in the pathogenesis of psoriasis and contact hypersensitivity, its role in atopic dermatitis is still unclear.
Lippincott Williams & Wilkins