Multicenter trial of cryotherapy for retinopathy of prematurity: preliminary results

… for Retinopathy of Prematurity Cooperative Group - …, 1988 - publications.aap.org
We report the preliminary 3-month outcome of a multicenter randomized trial of cryotherapy
for treatment of retinopathy of prematurity (ROP). Transscleral cryotherapy to the avascular
retina was applied to one randomly selected eye when there was threshold disease (defined
as five or more contiguous or eight cumulative 30° sectors [clock hours] of stage 3 ROP in
zone 1 or 2 in the presence of" plus" disease). An unfavorable outcome was defined as
posterior retinal detachment, retinal fold involving the macula, or retrolental tissue. At this …