Retrolental fibroplasia: cooperative study of retrolental fibroplasia and the use of oxygen

VE Kinsey, JT Jacobus… - AMA archives of …, 1956 - jamanetwork.com
(Footnotes continued on next page) Introduction Administration of oxygen to premature
infants had been implicated as an etiologic agent in the development of retrolental
fibroplasia (RLF) prior to late 1952.* But because of the apparently capricious fluctuation in
incidence of the disease observed in various communities and the insufficiency of controlled
investigations concerning the possible role of oxygen in RLF the evidence was deemed
inadequate to justify curtailment of oxygen for premature infants, particularly in the absence …