Treatment of deep-vein thrombosis

SM Bates, JS Ginsberg - New England Journal of Medicine, 2004 - Mass Medical Soc
New England Journal of Medicine, 2004Mass Medical Soc
Foreword This Journal feature begins with a case vignette highlighting a common clinical
problem. Evidence supporting various strategies is then presented, followed by a review of
formal guidelines, when they exist. The article ends with the authors' clinical
recommendations. Stage A 52-year-old-woman with no history of venous thromboembolism
presents with a four-day history of discomfort in her left calf. Proximal deep-vein thrombosis
is diagnosed by compression ultrasonography. How should her case be managed? The …
Foreword
This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the authors' clinical recommendations.
Stage
A 52-year-old-woman with no history of venous thromboembolism presents with a four-day history of discomfort in her left calf. Proximal deep-vein thrombosis is diagnosed by compression ultrasonography. How should her case be managed?
The Clinical Problem
The annual incidence of venous thromboembolism is approximately 0.1 percent; the rate increases from 0.01 percent among persons in early adulthood to nearly 1 percent among those who are at least 60 years old.1,2 More than half of these events involve deep-vein thrombosis. To minimize the risk of fatal pulmonary embolism, accurate diagnosis and prompt therapy are crucial.3 Long-term complications include the . . .
The New England Journal Of Medicine