Interferon-γ modulates the fibrinolytic response in cultured human endothelial cells
V Arnman, S Stemme, L Rymo, B Risberg - Thrombosis research, 1995 - Elsevier
The fibrinolytic potential of the endothelial cells gives important antithrombotic properties to
the vascular wall. Thrombosis is a frequent complication to atherosclerosis and other
conditions where inflammatory mediators are present in the vascular wall. Inflammatory
agents like lipopolysaccharide (LPS) and tumor necrosis factor-α (TNFα) have been
demonstrated to modulate the expression of fibrinolytic factors in cultured endothelial cells.
In the present study the expression of tissue-type plasminogen activator (t-PA), urokinase …
the vascular wall. Thrombosis is a frequent complication to atherosclerosis and other
conditions where inflammatory mediators are present in the vascular wall. Inflammatory
agents like lipopolysaccharide (LPS) and tumor necrosis factor-α (TNFα) have been
demonstrated to modulate the expression of fibrinolytic factors in cultured endothelial cells.
In the present study the expression of tissue-type plasminogen activator (t-PA), urokinase …