Consideration of sex differences in medicine to improve health care and patient outcomes
MJ Legato, PA Johnson, JAE Manson - Jama, 2016 - jamanetwork.com
Even though the observation that men and women are different is arguably as old as human
life, women have been included in clinical trials for only a few decades. Women have a
unique physiology and their experience of illness, and responses to therapeutic
interventions are often significantly different from those of men. Recent regulations from the
National Institutes of Health requiring grant applicants to consider sex as a variable in
biomedical research are a welcome development. 1 However, despite increasing evidence …
life, women have been included in clinical trials for only a few decades. Women have a
unique physiology and their experience of illness, and responses to therapeutic
interventions are often significantly different from those of men. Recent regulations from the
National Institutes of Health requiring grant applicants to consider sex as a variable in
biomedical research are a welcome development. 1 However, despite increasing evidence …