Eotaxin-2 and eotaxin-3 expression is associated with persistent eosinophilic bronchial inflammation in patients with asthma after allergen challenge
AJ Ravensberg, FLM Ricciardolo… - Journal of allergy and …, 2005 - Elsevier
BACKGROUND: Eotaxin-1, eotaxin-2, and eotaxin-3 are chemokines involved in the
activation and recruitment of eosinophils through activation of their main receptor, CC
chemokine receptor 3. The differential roles of these chemokines still remain to be
established. It has been suggested that eotaxin-1 is an important mediator in the early phase
of allergen-induced recruitment of eosinophils into the airways. Eotaxin-2 and eotaxin-3
might play a role in the subsequent persistence of allergen-induced bronchial eosinophilia …
activation and recruitment of eosinophils through activation of their main receptor, CC
chemokine receptor 3. The differential roles of these chemokines still remain to be
established. It has been suggested that eotaxin-1 is an important mediator in the early phase
of allergen-induced recruitment of eosinophils into the airways. Eotaxin-2 and eotaxin-3
might play a role in the subsequent persistence of allergen-induced bronchial eosinophilia …