[HTML][HTML] Rapid screening evaluation of SARS-CoV-2 IgG assays using Z-scores to standardize results
MK Das, A Chaudhary, A Bryan, MH Wener… - Emerging Infectious …, 2020 - ncbi.nlm.nih.gov
Emerging Infectious Diseases, 2020•ncbi.nlm.nih.gov
Many serologic tests are now available for measuring severe acute respiratory syndrome
coronavirus 2 antibodies to evaluate potential protective immunity and for seroprevalence
studies. We describe an approach to standardizing positivity thresholds and quantitative
values for different assays that uses z-scores to enable rapid and efficient comparison of
serologic test performance.
coronavirus 2 antibodies to evaluate potential protective immunity and for seroprevalence
studies. We describe an approach to standardizing positivity thresholds and quantitative
values for different assays that uses z-scores to enable rapid and efficient comparison of
serologic test performance.
Abstract
Many serologic tests are now available for measuring severe acute respiratory syndrome coronavirus 2 antibodies to evaluate potential protective immunity and for seroprevalence studies. We describe an approach to standardizing positivity thresholds and quantitative values for different assays that uses z-scores to enable rapid and efficient comparison of serologic test performance.
ncbi.nlm.nih.gov