[HTML][HTML] Alpha-oxidation
GA Jansen, RJA Wanders - Biochimica et Biophysica Acta (BBA)-Molecular …, 2006 - Elsevier
GA Jansen, RJA Wanders
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research, 2006•ElsevierPhytanic acid (3, 7, 11, 15-tetramethylhexadecanoic acid) is a branched chain fatty acid,
which is a constituent of the human diet. The presence of the 3-methyl group of phytanic acid
prevents degradation by beta-oxidation. Instead, the terminal carboxyl group is first removed
by alpha-oxidation. The mechanism of the alpha-oxidation pathway and the enzymes
involved are described in this review.
which is a constituent of the human diet. The presence of the 3-methyl group of phytanic acid
prevents degradation by beta-oxidation. Instead, the terminal carboxyl group is first removed
by alpha-oxidation. The mechanism of the alpha-oxidation pathway and the enzymes
involved are described in this review.
Phytanic acid (3,7,11,15-tetramethylhexadecanoic acid) is a branched chain fatty acid, which is a constituent of the human diet. The presence of the 3-methyl group of phytanic acid prevents degradation by beta-oxidation. Instead, the terminal carboxyl group is first removed by alpha-oxidation. The mechanism of the alpha-oxidation pathway and the enzymes involved are described in this review.
Elsevier
